Ukr.Biochem.J. 2023; Том 95, № 2, березень-квітень, c. 106-116

doi: https://doi.org/10.15407/ubj95.02.106

Лауреати нобелівської премії Арвід Карлссон, Пол Грінгард і Ерік Кендел: дослідження передачі сигналів у нервовій системі

Т. В. Данилова1,2*, С. В. Комісаренко3

1Інститут соціальної та політичної психології НАПН України, Київ;
2Вища школа соціальних досліджень, Інститут філософії та соціології
Польської академії наук, Варшава, Польща;
*e-mail: danilova_tv@ukr.net;
3Інститут біохімії ім. О. В. Палладіна НАН України, Київ;
e-mail: svk@biochem.kiev.ua

Отримано: 08 березня 2022; Виправлено: 11 квітня 2023;
Затверджено: 05 червня 2023; Доступно онлайн: 20 червня 2023

Багато десятиліть вчені намагаються розгадати таємниці складного феномену нервової системи, яка отримує повідомлення, обробляє інформацію та надсилає сигнали до різних органів. Найважливіші наукові відкриття 19-го та 20-го століть проклали шлях до Нобелівської премії з фізіології або медицини 2000 року, присудженої Арвіду Карлссону, Полу Грінгарду та Еріку Кенделу «за відкриття щодо передачі сигналів у нервовій системі». Отже, початок нового тисячоліття був “ознаменований” піонерськими дослідженнями хімічної передачі сигналів у центральній нервовій системі, що створили фундамент для глибшого розуміння медіаторної ролі дофаміну, процесів повільної синаптичної передачі, короткочасної та тривалої пам’яті, механізмів дії антипсихотичних та антидепресантних лікарських засобів. У статті представлено короткий огляд основних етапів наукової діяльності шведського нейрофармаколога Пера Арвіда Еміля Карлссона та американських нейробіологів Пола Грінгарда та Еріка Річарда Кендела.

Ключові слова: , , , , , , , , ,


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