Ukr.Biochem.J. 2013; Том 85, № 6, листопад-грудень, c. 53-74

doi: http://dx.doi.org/10.15407/ubj85.06.053

Імуносупресія під час вагітності і ризики за вірусних інфекцій

19.04.2016   Без категорії   No comments

О. І. Кисельов

ФГБУ «НДІ грипу» Мінздравсоцрозвитку РФ, С.-Петербург

Стаття присвячена дослідженням меха­нізмів сполученої імуносупресії у вагітних жінок із грипозною інфекцією для розробки заходів керування цими процесами і зниження смертності від цієї інфекції. У зв’язку з цим автор в огляді зупиняється на питаннях: яким чином забезпечується імунна перевага плода і розвиток толерантності; які механізми є основою функціональної імуносупресії під час вагітності; чому інфекції становлять особливу небезпеку для вагітних жінок; чи існує код контролю імунної системи і чи користуються цим кодом віруси?
Розглядається також проблема впливу ендогенних вірусів, вбудованих в геном людини більше 25 млн. років тому, на значне число ризиків розвитку різних видів патології людини: від безпліддя – до хвороб вагітності; від розвитку злоякісних новоутворень – до системної патології та автоімунних процесів.

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