Ukr.Biochem.J. 2021; Том 93, № 4, липень-серпень, c. 5-17
doi: doi: https://doi.org/10.15407/ubj93.04.005
Хлоридзв’язувальні структури, їх роль та організація в протеїнах
Р. Ю. Марунич*, А. А. Грабовський, Г. К. Березницький,
Л. В. Пирогова, Г. К. Гоголінська, Є. М. Макогоненко
Інститут біохімії ім. О.В. Палладіна НАН України, Київ;
*e-mail: rostmarbiotech@gmail.com
Отримано: 29 вересня 2020; Затверджено: 07 липня 2021
Огляд присвячено хлоридзв’язувальним структурам у складі протеїнів бактерій, рослин, вірусів та тварин. Розглянуто будову та амінокислотний склад хлоридзв’язувального сайту та його роль у функціонуванні структурних, регуляторних, транспортних, рецепторних, канальних протеїнів, а також транскрипційних факторів та ензимів. Наведено дані про важливу роль хлоридзв’язувальних структур і аніонів хлориду в полімеризації фібрину.
Ключові слова: структура протеїну, фібрин, хлорид-аніон, хлоридзв’язувальний сайт
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