Ukr.Biochem.J. 2017; Том 89, № 1, січень-лютий, c. 5-21

doi: https://doi.org/10.15407/ubj89.01.005

Ліпоксигенази та їхні метаболіти у формуванні стресостійкості рослин

22.02.2017   Без категорії   No comments

Л. М. Бабенко1, М. М. Щербатюк1, Т. Д. Скатерна2, І. В. Косаківська1

1Інститут ботаніки ім. М. Г. Холодного НАН України, Київ;
2Інститут біохімії ім, О. В. Палладіна НАН України, Київ;
e-mail: lilia.babenko@gmail.com

В огляді наведено дані літератури останніх років із молекулярної ензимології ліпоксигеназ – протеїнів, задіяних у реакціях пероксидного окислення ліпідів і знайдених у тварин і рослин. Розглянуто й узагальнено існуючі уявлення щодо особливостей будови, каталітичних властивостей та функціонування ензимів родини ліпоксигеназ і продуктів їхньої каталітичної активності в рослинах. Обговорюються питання локалізації ензиму в рослинних клітинах і тканинах, еволюції та розповсюдження ліпоксигеназ, участі в утворенні сигнальних речовин, задіяних у формуванні адаптаційної відповіді на абіотичні та біотичні стресорні чинники, а також регуляції активності ліпоксигеназної (ЛОГ) сигнальної системи. Розглянуто елементи процесів рецепції та трансдукції сигналів ЛОГ-шляху до геному. Особливу увагу приділено жасмонатам, метаболітам аленоксидсинтазної гілки ліпоксигеназного каскаду. Ці метаболіти виявляють високу біологічну активність, повсюдно поширені в рослинних організмах, а також беруть участь у регуляції життєво важливих процесів. Проаналізовано результати щодо філогенії ліпоксигеназ, можливості існування спільного попередника сучасних ізоформ ензиму про/евкаріот. Подано окремі результати власних досліджень авторів стосовно використання показників каталітичної активності ліпоксигеназ як біологічних маркерів під час дослідження стресостійкості рослин.

Ключові слова: , , , ,

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